BDBM50005257 (+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine::(+)2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine::(+/-)2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine::(-)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine::(-)2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine::1-(4-bromo-2,5-dimethoxyphenyl)propan-2-amine::2-(2-Methoxy-phenyl)-1-methyl-ethylamine::2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine::2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine((-)-DOB)::2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine((R)-(-)-DOB)::2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine((S)-(+)-DOB)::2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine(DOB)::2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine[R(-)DOB]::2-(5-Bromo-2,4-dimethoxy-phenyl)-1-methyl-ethylamine::Brolamfetamine::CHEMBL6607::DOB::Racemic DOB

SMILES COc1cc(CC(C)N)c(OC)cc1Br

InChI Key InChIKey=FXMWUTGUCAKGQL-UHFFFAOYSA-N

Data  52 KI  1 IC50  1 Kd  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50005257   

Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM50005257((+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethy...)
Affinity DataKi:  1.30nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50005257((+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethy...)
Affinity DataKi:  2.80nMAssay Description:In vitro binding to 5-hydroxytryptamine 2C receptor using [125 I]-DOIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50005257((+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethy...)
Affinity DataKi:  2.80nMAssay Description:Binding affinity at cloned rat 5-hydroxytryptamine 2C receptor using [3H]-DOI as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50005257((+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethy...)
Affinity DataKi:  3.01nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM50005257((+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethy...)
Affinity DataKi:  6.31nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM50005257((+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethy...)
Affinity DataKi:  7.76nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50005257((+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethy...)
Affinity DataKi:  10nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50005257((+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethy...)
Affinity DataKi:  10nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50005257((+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethy...)
Affinity DataKi:  60.3nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50005257((+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethy...)
Affinity DataKi:  64nMAssay Description:Displacement of [3H]-mesulergine from A9 cells stably expressing rat 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50005257((+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethy...)
Affinity DataKi:  70nMAssay Description:The compound evaluated for its affinity against 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50005257((+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethy...)
Affinity DataKi:  70nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1C receptor from frontal cortical regions of male Sprague-Dawley rat homogenates, using [3H]mesulergine ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50005257((+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethy...)
Affinity DataKi:  152nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50005257((+)-2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethy...)
Affinity DataKi:  152nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed